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Different agonists induce distinct single-channel conductance states in TRPV1 channels

The TRPV1 ion channel is a membrane protein that is expressed in primary afferent nociceptors, where it is activated by a diverse array of stimuli. Our prior work has shown that this channel is activated by lysophosphatidic acid (LPA), an unsaturated lysophospholipid that is produced endogenously an...

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Detalles Bibliográficos
Autores principales: Canul-Sánchez, Jesús Aldair, Hernández-Araiza, Ileana, Hernández-García, Enrique, Llorente, Itzel, Morales-Lázaro, Sara L., Islas, León D., Rosenbaum, Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279355/
https://www.ncbi.nlm.nih.gov/pubmed/30409787
http://dx.doi.org/10.1085/jgp.201812141

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