TREK-1 channels regulate pressure sensitivity and calcium signaling in trabecular meshwork cells

Mechanotransduction by the trabecular meshwork (TM) is an essential component of intraocular pressure regulation in the vertebrate eye. This process is compromised in glaucoma but is poorly understood. In this study, we identify transient receptor potential vanilloid isoform 4 (TRPV4) and TWIK-relat...

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Detalles Bibliográficos
Autores principales: Yarishkin, Oleg, Phuong, Tam T.T., Bretz, Colin A., Olsen, Kenneth W., Baumann, Jackson M., Lakk, Monika, Crandall, Alan, Heurteaux, Catherine, Hartnett, Mary E., Križaj, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279358/
https://www.ncbi.nlm.nih.gov/pubmed/30446509
http://dx.doi.org/10.1085/jgp.201812179

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