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Cargo regulates clathrin-coated pit invagination via clathrin light chain phosphorylation
Clathrin light chains (CLCs) control selective uptake of a range of G protein–coupled receptors (GPCRs), although the mechanism by which this occurs has remained elusive thus far. In particular, site-specific phosphorylation of CLCb controls the uptake of the purinergic GPCR P2Y(12), but it is dispe...
Autores principales: | Maib, Hannes, Ferreira, Filipe, Vassilopoulos, Stéphane, Smythe, Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279376/ https://www.ncbi.nlm.nih.gov/pubmed/30228161 http://dx.doi.org/10.1083/jcb.201805005 |
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