Kinesin-binding–triggered conformation switching of microtubules contributes to polarized transport

Kinesin-1, the founding member of the kinesin superfamily of proteins, is known to use only a subset of microtubules for transport in living cells. This biased use of microtubules is proposed as the guidance cue for polarized transport in neurons, but the underlying mechanisms are still poorly under...

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Detalles Bibliográficos
Autores principales: Shima, Tomohiro, Morikawa, Manatsu, Kaneshiro, Junichi, Kambara, Taketoshi, Kamimura, Shinji, Yagi, Toshiki, Iwamoto, Hiroyuki, Uemura, Sotaro, Shigematsu, Hideki, Shirouzu, Mikako, Ichimura, Taro, Watanabe, Tomonobu M., Nitta, Ryo, Okada, Yasushi, Hirokawa, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279379/
https://www.ncbi.nlm.nih.gov/pubmed/30297389
http://dx.doi.org/10.1083/jcb.201711178

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