EHD2 is a mechanotransducer connecting caveolae dynamics with gene transcription

Caveolae are small invaginated pits that function as dynamic mechanosensors to buffer tension variations at the plasma membrane. Here we show that under mechanical stress, the EHD2 ATPase is rapidly released from caveolae, SUMOylated, and translocated to the nucleus, where it regulates the transcrip...

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Detalles Bibliográficos
Autores principales: Torrino, Stéphanie, Shen, Wei-Wei, Blouin, Cédric M., Mani, Satish Kailasam, Viaris de Lesegno, Christine, Bost, Pierre, Grassart, Alexandre, Köster, Darius, Valades-Cruz, Cesar Augusto, Chambon, Valérie, Johannes, Ludger, Pierobon, Paolo, Soumelis, Vassili, Coirault, Catherine, Vassilopoulos, Stéphane, Lamaze, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279385/
https://www.ncbi.nlm.nih.gov/pubmed/30348749
http://dx.doi.org/10.1083/jcb.201801122

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