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Cryo–electron microscopy structure of the lipid droplet–formation protein seipin

Metabolic energy is stored in cells primarily as triacylglycerols in lipid droplets (LDs), and LD dysregulation leads to metabolic diseases. The formation of monolayer-bound LDs from the endoplasmic reticulum (ER) bilayer is poorly understood, but the ER protein seipin is essential to this process....

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Detalles Bibliográficos
Autores principales:	Sui, Xuewu, Arlt, Henning, Brock, Kelly P., Lai, Zon Weng, DiMaio, Frank, Marks, Debora S., Liao, Maofu, Farese, Robert V., Walther, Tobias C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279392/ https://www.ncbi.nlm.nih.gov/pubmed/30327422 http://dx.doi.org/10.1083/jcb.201809067

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