IgM’s exit route

In this issue of JEM, Thierry et al. (https://doi.org/10.1084/jem.20180344) demonstrate that, once secreted by freshly activated plasmablasts, IgM leaves the lymph node via the microarchitecture of the fibroblastic reticular cell conduit. This work demonstrates how the very peculiar stromal compartm...

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Detalles Bibliográficos
Autores principales: Reversat, Anne, Sixt, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279393/
https://www.ncbi.nlm.nih.gov/pubmed/30459158
http://dx.doi.org/10.1084/jem.20181934
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author Reversat, Anne
Sixt, Michael
author_facet Reversat, Anne
Sixt, Michael
author_sort Reversat, Anne
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description In this issue of JEM, Thierry et al. (https://doi.org/10.1084/jem.20180344) demonstrate that, once secreted by freshly activated plasmablasts, IgM leaves the lymph node via the microarchitecture of the fibroblastic reticular cell conduit. This work demonstrates how the very peculiar stromal compartment of lymphatic organs optimizes the systemic distribution of immune effectors.
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spelling pubmed-62793932019-06-03 IgM’s exit route Reversat, Anne Sixt, Michael J Exp Med News In this issue of JEM, Thierry et al. (https://doi.org/10.1084/jem.20180344) demonstrate that, once secreted by freshly activated plasmablasts, IgM leaves the lymph node via the microarchitecture of the fibroblastic reticular cell conduit. This work demonstrates how the very peculiar stromal compartment of lymphatic organs optimizes the systemic distribution of immune effectors. Rockefeller University Press 2018-12-03 /pmc/articles/PMC6279393/ /pubmed/30459158 http://dx.doi.org/10.1084/jem.20181934 Text en © 2018 Reversat and Sixt http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Reversat, Anne
Sixt, Michael
IgM’s exit route
title IgM’s exit route
title_full IgM’s exit route
title_fullStr IgM’s exit route
title_full_unstemmed IgM’s exit route
title_short IgM’s exit route
title_sort igm’s exit route
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279393/
https://www.ncbi.nlm.nih.gov/pubmed/30459158
http://dx.doi.org/10.1084/jem.20181934
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