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CNBP controls IL-12 gene transcription and Th1 immunity
An inducible program of inflammatory gene expression is a hallmark of antimicrobial defenses. Recently, cellular nucleic acid–binding protein (CNBP) was identified as a regulator of nuclear factor-kappaB (NF-κB)–dependent proinflammatory cytokine gene expression. Here, we generated mice lacking CNBP...
Autores principales: | Chen, Yongzhi, Sharma, Shruti, Assis, Patricia A., Jiang, Zhaozhao, Elling, Roland, Olive, Andrew J., Hang, Saiyu, Bernier, Jennifer, Huh, Jun R., Sassetti, Christopher M., Knipe, David M., Gazzinelli, Ricardo T., Fitzgerald, Katherine A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279399/ https://www.ncbi.nlm.nih.gov/pubmed/30442645 http://dx.doi.org/10.1084/jem.20181031 |
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