IFNγ-activated dermal lymphatic vessels inhibit cytotoxic T cells in melanoma and inflamed skin

Mechanisms of immune suppression in peripheral tissues counteract protective immunity to prevent immunopathology and are coopted by tumors for immune evasion. While lymphatic vessels facilitate T cell priming, they also exert immune suppressive effects in lymph nodes at steady-state. Therefore, we h...

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Detalles Bibliográficos
Autores principales: Lane, Ryan S., Femel, Julia, Breazeale, Alec P., Loo, Christopher P., Thibault, Guillaume, Kaempf, Andy, Mori, Motomi, Tsujikawa, Takahiro, Chang, Young Hwan, Lund, Amanda W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279400/
https://www.ncbi.nlm.nih.gov/pubmed/30381467
http://dx.doi.org/10.1084/jem.20180654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279400/
https://www.ncbi.nlm.nih.gov/pubmed/30381467
http://dx.doi.org/10.1084/jem.20180654

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