Sensing danger through a “finger”

In this issue of JEM, the study by Chen et al. (https://doi.org/10.1084/jem.20181031) reveals a previously unrecognized role of cellular nucleic acid–binding protein (Cnbp) as a novel transcriptional regulator of interleukin-12β (IL-12β) transcription and IL-12–driven, Th1-mediated immune responses,...

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Detalles Bibliográficos
Autor principal: Ma, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279409/
https://www.ncbi.nlm.nih.gov/pubmed/30459157
http://dx.doi.org/10.1084/jem.20182034
Descripción
Sumario:In this issue of JEM, the study by Chen et al. (https://doi.org/10.1084/jem.20181031) reveals a previously unrecognized role of cellular nucleic acid–binding protein (Cnbp) as a novel transcriptional regulator of interleukin-12β (IL-12β) transcription and IL-12–driven, Th1-mediated immune responses, which has important implications for both host defense and inflammatory disease.

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