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Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1
The mammalian cochlea contains two types of mechanosensory hair cells (HCs) that play different and critical roles in hearing. Inner hair cells (IHCs), with an elaborate presynaptic apparatus, signal to cochlear neurons and communicate sound information to the brain. Outer hair cells (OHCs) mechanic...
Autores principales: | Wiwatpanit, Teerawat, Lorenzen, Sarah M., Cantú, Jorge A., Foo, Chuan Zhi, Hogan, Ann K., Márquez, Freddie, Clancy, John C., Schipma, Matthew J., Cheatham, Mary Ann, Duggan, Anne, García-Añoveros, Jaime |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279423/ https://www.ncbi.nlm.nih.gov/pubmed/30305733 http://dx.doi.org/10.1038/s41586-018-0570-8 |
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