Tuning of human MAIT cell activation by commensal bacteria species and MR1 dependent T cell presentation

Human mucosal-associated invariant T (MAIT) cell receptors (TCRs) recognize bacterial riboflavin pathway metabolites through the MHC class 1-related molecule MR1. However, it is unclear whether MAIT cells discriminate between many species of the human microbiota. To address this, we developed an in...

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Detalles Bibliográficos
Autores principales: Tastan, Cihan, Karhan, Ece, Zhou, Wei, Fleming, Elizabeth, Voigt, Anita Y., Yao, Xudong, Wang, Lei, Horne, Meghan, Placek, Lindsey, Kozhaya, Lina, Oh, Julia, Unutmaz, Derya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279574/
https://www.ncbi.nlm.nih.gov/pubmed/30115998
http://dx.doi.org/10.1038/s41385-018-0072-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279574/
https://www.ncbi.nlm.nih.gov/pubmed/30115998
http://dx.doi.org/10.1038/s41385-018-0072-x

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