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New mechanisms of phenytoin in calcium homeostasis: competitive inhibition of CD38 in hippocampal cells
PURPOSE: Phenytoin is a major anticonvulsant drug that is effective to improve arrhythmia and neuropathic pain. According to early works, phenytoin affected cell membrane depolarization by sodium channel blocking, guanylyl and adenylyl cyclase suppression that cause to intracellular Na(+) and Ca(2+)...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279657/ https://www.ncbi.nlm.nih.gov/pubmed/30402721 http://dx.doi.org/10.1007/s40199-018-0224-2 |