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Nicotinamide loaded functionalized solid lipid nanoparticles improves cognition in Alzheimer’s disease animal model by reducing Tau hyperphosphorylation

BACKGROUND: Nicotinamide is considered to be effective in halting the Alzheimer’s disease progression. The body could absorb a limited amount of nicotinamide at a time, requiring multiple doses through a day. To overcome such an obstacle which reduces the patient compliance, a sustained/controlled d...

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Detalles Bibliográficos
Autores principales: Vakilinezhad, Molood Alsadat, Amini, Azadeh, Akbari Javar, Hamid, Baha’addini Beigi Zarandi, Batool Faegheh, Montaseri, Hashem, Dinarvand, Rassoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279660/
https://www.ncbi.nlm.nih.gov/pubmed/30386982
http://dx.doi.org/10.1007/s40199-018-0221-5