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Effects of metformin on the PI3K/AKT/FOXO1 pathway in anaplastic thyroid Cancer cell lines

BACKGROUND: The PI3K/AKT/FOXO signaling pathway plays an important role in the survival, proliferation and apoptosis of tumor cells. The aim of the present study was to explore whether metformin could affect insulin-promoting cell growth by regulation of this pathway. MATERIAL AND METHODS: Anaplasti...

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Detalles Bibliográficos
Autores principales:	Nozhat, Zahra, Mohammadi-Yeganeh, Samira, Azizi, Feridoun, Zarkesh, Maryam, Hedayati, Mehdi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279666/ https://www.ncbi.nlm.nih.gov/pubmed/30242671 http://dx.doi.org/10.1007/s40199-018-0208-2

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