A near atomic-scale view at the composition of amyloid-beta fibrils by atom probe tomography

Amyloid-beta (Ab) proteins play an important role in a number of neurodegenerative diseases. Ab is found in senile plaques in brains of Alzeimer’s disease patients. The 42 residues of the monomer form dimers which stack to fibrils gaining several micrometers in length. Using Ab fibrils with (13)C an...

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Detalles Bibliográficos
Autores principales: Rusitzka, Kristiane A. K., Stephenson, Leigh T., Szczepaniak, Agnieszka, Gremer, Lothar, Raabe, Dierk, Willbold, Dieter, Gault, Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279744/
https://www.ncbi.nlm.nih.gov/pubmed/30514971
http://dx.doi.org/10.1038/s41598-018-36110-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279744/
https://www.ncbi.nlm.nih.gov/pubmed/30514971
http://dx.doi.org/10.1038/s41598-018-36110-y

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