Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

Cancer-associated fibroblasts (CAFs) are a major constituent of the tumor microenvironment, although their origin and roles in shaping disease initiation, progression and treatment response remain unclear due to significant heterogeneity. Here, following a negative selection strategy combined with s...

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Detalles Bibliográficos
Autores principales: Bartoschek, Michael, Oskolkov, Nikolay, Bocci, Matteo, Lövrot, John, Larsson, Christer, Sommarin, Mikael, Madsen, Chris D., Lindgren, David, Pekar, Gyula, Karlsson, Göran, Ringnér, Markus, Bergh, Jonas, Björklund, Åsa, Pietras, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279758/
https://www.ncbi.nlm.nih.gov/pubmed/30514914
http://dx.doi.org/10.1038/s41467-018-07582-3

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