3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

The podocytes within the glomeruli of the kidney maintain the filtration barrier by forming interdigitating foot processes with intervening slit diaphragms, disruption in which results in proteinuria. Studies into human podocytopathies to date have employed primary or immortalised podocyte cell line...

Descripción completa

Detalles Bibliográficos
Autores principales: Hale, Lorna J., Howden, Sara E., Phipson, Belinda, Lonsdale, Andrew, Er, Pei X., Ghobrial, Irene, Hosawi, Salman, Wilson, Sean, Lawlor, Kynan T., Khan, Shahnaz, Oshlack, Alicia, Quinlan, Catherine, Lennon, Rachel, Little, Melissa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279764/
https://www.ncbi.nlm.nih.gov/pubmed/30514835
http://dx.doi.org/10.1038/s41467-018-07594-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279764/
https://www.ncbi.nlm.nih.gov/pubmed/30514835
http://dx.doi.org/10.1038/s41467-018-07594-z

Ejemplares similares