Single-cell mutation identification via phylogenetic inference

Reconstructing the evolution of tumors is a key aspect towards the identification of appropriate cancer therapies. The task is challenging because tumors evolve as heterogeneous cell populations. Single-cell sequencing holds the promise of resolving the heterogeneity of tumors; however, it has its o...

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Detalles Bibliográficos
Autores principales: Singer, Jochen, Kuipers, Jack, Jahn, Katharina, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279798/
https://www.ncbi.nlm.nih.gov/pubmed/30514897
http://dx.doi.org/10.1038/s41467-018-07627-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279798/
https://www.ncbi.nlm.nih.gov/pubmed/30514897
http://dx.doi.org/10.1038/s41467-018-07627-7

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