Data highlighting the expression of two miR-132/212 target genes—Sirt1 and Pten—after chronic stress

The data presented here are related to our research article entitled “miR-132/212 is induced by stress and its dysregulation triggers anxiety-related behavior” (Aten et al., 2018). In this article, we utilize immunofluorescent techniques to examine the protein-level expression of two microRNA-132/21...

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Detalles Bibliográficos
Autores principales: Aten, Sydney, Page, Chloe E., Kalidindi, Anisha, Wheaton, Kelin L., Niraula, Anzela, Godbout, Jon P., Hoyt, Kari R., Obrietan, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279806/
https://www.ncbi.nlm.nih.gov/pubmed/30555870
http://dx.doi.org/10.1016/j.dib.2018.11.042
Descripción
Sumario:The data presented here are related to our research article entitled “miR-132/212 is induced by stress and its dysregulation triggers anxiety-related behavior” (Aten et al., 2018). In this article, we utilize immunofluorescent techniques to examine the protein-level expression of two microRNA-132/212 target genes, Sirt1 and Pten, in miR-132 transgenic and miR-132/212 conditional knockout (cKO) mouse lines. Additionally, using immunohistochemistry, we detail the expression profile of Sirt1 and Pten in the hippocampus and amygdala of WT mice after a 15 day chronic restraint stress paradigm.

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