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The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background

The predisposition of parasites acquiring artemisinin resistance still remains unclear beyond the mutations in Pfk13 gene and modulation of the unfolded protein response pathway. To explore the chain of casualty underlying artemisinin resistance, we reanalyze 773 P. falciparum isolates from TRACI-st...

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Detalles Bibliográficos
Autores principales: Zhu, Lei, Tripathi, Jaishree, Rocamora, Frances Maureen, Miotto, Olivo, van der Pluijm, Rob, Voss, Till S., Mok, Sachel, Kwiatkowski, Dominic P., Nosten, François, Day, Nicholas P. J., White, Nicholas J., Dondorp, Arjen M., Bozdech, Zbynek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279830/
https://www.ncbi.nlm.nih.gov/pubmed/30514877
http://dx.doi.org/10.1038/s41467-018-07588-x