Downregulation of Neuronal and Dendritic Connexin36-Made Electrical Synapses Without Glutamatergic Axon Terminals in Spinal Anterior Horn Cells From the Early Stage of Amyotrophic Lateral Sclerosis

Connexin36 (Cx36) forms gap junctions between neurons, which are called electrical synapses, enabling adjacent neurons to communicate directly. The participation of chemical synapses in neurodegeneration in amyotrophic lateral sclerosis (ALS) has long been indicated, but it remains unclear whether e...

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Detalles Bibliográficos
Autores principales: Kobayakawa, Yuko, Masaki, Katsuhisa, Yamasaki, Ryo, Shiraishi, Wataru, Hayashida, Shotaro, Hayashi, Shintaro, Okamoto, Koichi, Matsushita, Takuya, Kira, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279874/
https://www.ncbi.nlm.nih.gov/pubmed/30546295
http://dx.doi.org/10.3389/fnins.2018.00894

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