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Isoorientin Ameliorates APAP-Induced Hepatotoxicity via Activation Nrf2 Antioxidative Pathway: The Involvement of AMPK/Akt/GSK3β

Oxidative stress has been highlighted as therapeutic targets for acetaminophen (APAP)-induced hepatotoxicity. Isoorientin (Iso), a well-known flavonoid-like compound, has been shown to have antioxidant potential. However, the effect of Iso on APAP-induced liver injury has not yet been elucidated. Th...

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Detalles Bibliográficos
Autores principales:	Fan, Xiaoye, Lv, Hongming, Wang, Lidong, Deng, Xuming, Ci, Xinxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279939/ https://www.ncbi.nlm.nih.gov/pubmed/30546306 http://dx.doi.org/10.3389/fphar.2018.01334

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