Transvaginal fast-scanning optical-resolution photoacoustic endoscopy

Photoacoustic endoscopy offers in vivo examination of the visceral tissue using endogenous contrast, but its typical B-scan rate is [Formula: see text] , restricted by the speed of the scanning unit and the laser pulse repetition rate. Here, we present a transvaginal fast-scanning optical-resolution...

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Detalles Bibliográficos
Autores principales: Qu, Yuan, Li, Chiye, Shi, Junhui, Chen, Ruimin, Xu, Song, Rafsanjani, Hasan, Maslov, Konstantin, Krigman, Hannah, Garvey, Laura, Hu, Peng, Zhao, Peinan, Meyers, Karen, Diveley, Emily, Pizzella, Stephanie, Muench, Lisa, Punyamurthy, Nina, Goldstein, Naomi, Onwumere, Oji, Alisio, Mariana, Meyenburg, Kaytelyn, Maynard, Jennifer, Helm, Kristi, Slaughter, Janessia, Barber, Sabrina, Burger, Tracy, Kramer, Christine, Chubiz, Jessica, Anderson, Monica, McCarthy, Ronald, England, Sarah K., Macones, George A., Zhou, Qifa, Shung, K. Kirk, Zou, Jun, Stout, Molly J., Tuuli, Methodius, Wang, Lihong V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2018
Materias:
Special Section on Laser-Tissue Interaction and Optical Properties of Biological Tissues: Honoring Prof. Steven Jacques, a Pioneer in Biomedical Optics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279961/
https://www.ncbi.nlm.nih.gov/pubmed/30520276
http://dx.doi.org/10.1117/1.JBO.23.12.121617
Descripción
Sumario:Photoacoustic endoscopy offers in vivo examination of the visceral tissue using endogenous contrast, but its typical B-scan rate is [Formula: see text] , restricted by the speed of the scanning unit and the laser pulse repetition rate. Here, we present a transvaginal fast-scanning optical-resolution photoacoustic endoscope with a 250-Hz B-scan rate over a 3-mm scanning range. Using this modality, we not only illustrated the morphological differences of vasculatures among the human ectocervix, uterine body, and sublingual mucosa but also showed the longitudinal and cross-sectional differences of cervical vasculatures in pregnant women. This technology is promising for screening the visceral pathological changes associated with angiogenesis.

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