BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication

BET bromodomain proteins are required for oncogenic transcription activities, and BET inhibitors have been rapidly advanced into clinical trials. Understanding the effects of BET inhibition on processes such as DNA replication will be important for future clinical applications. Here, we show that BE...

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Detalles Bibliográficos
Autores principales: Bowry, Akhil, Piberger, Ann Liza, Rojas, Patricia, Saponaro, Marco, Petermann, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280123/
https://www.ncbi.nlm.nih.gov/pubmed/30463005
http://dx.doi.org/10.1016/j.celrep.2018.10.079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280123/
https://www.ncbi.nlm.nih.gov/pubmed/30463005
http://dx.doi.org/10.1016/j.celrep.2018.10.079

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