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BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication
BET bromodomain proteins are required for oncogenic transcription activities, and BET inhibitors have been rapidly advanced into clinical trials. Understanding the effects of BET inhibition on processes such as DNA replication will be important for future clinical applications. Here, we show that BE...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280123/ https://www.ncbi.nlm.nih.gov/pubmed/30463005 http://dx.doi.org/10.1016/j.celrep.2018.10.079 |