Sprouty2 enhances the tumorigenic potential of glioblastoma cells

BACKGROUND: Sprouty2 (SPRY2), a feedback regulator of receptor tyrosine kinase (RTK) signaling, has been shown to be associated with drug resistance and cell proliferation in glioblastoma (GBM), but the underlying mechanisms are still poorly defined. METHODS: SPRY2 expression and survival patterns o...

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Detalles Bibliográficos
Autores principales: Park, Jong-Whi, Wollmann, Guido, Urbiola, Carles, Fogli, Barbara, Florio, Tullio, Geley, Stephan, Klimaschewski, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280149/
https://www.ncbi.nlm.nih.gov/pubmed/29635363
http://dx.doi.org/10.1093/neuonc/noy028

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