Novel insights in the prevention of perinatal transmission of hepatitis B

Perinatal transmission of hepatitis B virus (HBV) infection is major contributor to the growing burden of chronic hepatitis B worldwide. Administration of HBV immunoglobulin and HBV vaccination as soon after pregnancy as possible are the mainstay of prevention of perinatal transmission of HBV infect...

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Autores principales: Tziomalos, Konstantinos, Neokosmidis, Georgios, Mavromatidis, Georgios, Dinas, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280156/
https://www.ncbi.nlm.nih.gov/pubmed/30533180
http://dx.doi.org/10.4254/wjh.v10.i11.795
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author Tziomalos, Konstantinos
Neokosmidis, Georgios
Mavromatidis, Georgios
Dinas, Konstantinos
author_facet Tziomalos, Konstantinos
Neokosmidis, Georgios
Mavromatidis, Georgios
Dinas, Konstantinos
author_sort Tziomalos, Konstantinos
collection PubMed
description Perinatal transmission of hepatitis B virus (HBV) infection is major contributor to the growing burden of chronic hepatitis B worldwide. Administration of HBV immunoglobulin and HBV vaccination as soon after pregnancy as possible are the mainstay of prevention of perinatal transmission of HBV infection. In women with high viral loads, antiviral prophylaxis also appears to be useful. Lamivudine, telbivudine and tenofovir have been shown to be both safe and effective in this setting but tenofovir is the first-line option due to its low potential for resistance and more favorable safety profile.
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spelling pubmed-62801562018-12-07 Novel insights in the prevention of perinatal transmission of hepatitis B Tziomalos, Konstantinos Neokosmidis, Georgios Mavromatidis, Georgios Dinas, Konstantinos World J Hepatol Editorial Perinatal transmission of hepatitis B virus (HBV) infection is major contributor to the growing burden of chronic hepatitis B worldwide. Administration of HBV immunoglobulin and HBV vaccination as soon after pregnancy as possible are the mainstay of prevention of perinatal transmission of HBV infection. In women with high viral loads, antiviral prophylaxis also appears to be useful. Lamivudine, telbivudine and tenofovir have been shown to be both safe and effective in this setting but tenofovir is the first-line option due to its low potential for resistance and more favorable safety profile. Baishideng Publishing Group Inc 2018-11-27 2018-11-27 /pmc/articles/PMC6280156/ /pubmed/30533180 http://dx.doi.org/10.4254/wjh.v10.i11.795 Text en ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Editorial
Tziomalos, Konstantinos
Neokosmidis, Georgios
Mavromatidis, Georgios
Dinas, Konstantinos
Novel insights in the prevention of perinatal transmission of hepatitis B
title Novel insights in the prevention of perinatal transmission of hepatitis B
title_full Novel insights in the prevention of perinatal transmission of hepatitis B
title_fullStr Novel insights in the prevention of perinatal transmission of hepatitis B
title_full_unstemmed Novel insights in the prevention of perinatal transmission of hepatitis B
title_short Novel insights in the prevention of perinatal transmission of hepatitis B
title_sort novel insights in the prevention of perinatal transmission of hepatitis b
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280156/
https://www.ncbi.nlm.nih.gov/pubmed/30533180
http://dx.doi.org/10.4254/wjh.v10.i11.795
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