EGF/EGFR upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence

BACKGROUND: Glioblastoma multiforme (GBM) is the most malignant central nervous system tumor. Alkylating agent, temozolomide (TMZ), is currently the first-line chemotherapeutic agent for GBM. However, the sensitivity of GBM cells to TMZ is affected by many factors. And, several clinic trials, includ...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Li, Huang, Yulun, Gao, Yuge, Shi, Tengfei, Xu, Yunyun, Li, Huini, Hyytiäinen, Marko, Keski-Oja, Jorma, Jiang, Qiuying, Hu, Yizhou, Du, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280426/
https://www.ncbi.nlm.nih.gov/pubmed/30514230
http://dx.doi.org/10.1186/s12885-018-5056-4

Ejemplares similares

Ejemplares similares