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MEF2 plays a significant role in the tumor inhibitory mechanism of encapsulated RENCA cells via EGF receptor signaling in target tumor cells

BACKGROUND: Agarose encapsulated murine renal adenocarcinoma cells (RENCA macrobeads) are currently being investigated in clinical trials as a treatment for therapy-resistant metastatic colorectal cancer. We have previously demonstrated the capacity of RENCA macrobeads to produce diffusible substanc...

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Detalles Bibliográficos
Autores principales: Martis, Prithy C., Dudley, Atira T., Bemrose, Melissa A., Gazda, Hunter L., Smith, Barry H., Gazda, Lawrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280513/
https://www.ncbi.nlm.nih.gov/pubmed/30514247
http://dx.doi.org/10.1186/s12885-018-5128-5