Promoter hypomethylation mediated upregulation of MicroRNA-10b-3p targets FOXO3 to promote the progression of esophageal squamous cell carcinoma (ESCC)

BACKGROUND: Esophageal cancer is a high incident cancer worldwide with poor survival and limited therapeutic options. Alterations of microRNAs are common in cancers, and many of these micro RNAs are potential therapeutic and diagnostic targets to treat these cancers. miR-10b-3p located in chromosome...

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Detalles Bibliográficos
Autores principales: Lu, Yi-fang, Yu, Jia-rui, Yang, Zhao, Zhu, Guan-xia, Gao, Peng, Wang, Huan, Chen, Si-yuan, Zhang, Jie, Liu, Mei-yue, Niu, Yi, Wei, Xiao-mei, Wang, Wei, Ye, Feng-jin, Zhang, Li-xin, Zhao, Yue, Sun, Guo-gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280546/
https://www.ncbi.nlm.nih.gov/pubmed/30514328
http://dx.doi.org/10.1186/s13046-018-0966-1

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