Mechanistic Insights From Global Metabolomics Studies into Synergistic Bactericidal Effect of a Polymyxin B Combination With Tamoxifen Against Cystic Fibrosis MDR Pseudomonas aeruginosa

Polymyxins are amongst the most important antibiotics in modern medicine, in recent times their clinical utility has been overshadowed by nosocomial outbreaks of polymyxin resistant MDR Gram-negative ‘superbugs’. An effective strategy to surmount polymyxin resistance is combination therapy with FDA-...

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Detalles Bibliográficos
Autores principales: Hussein, Maytham, Han, Mei-Ling, Zhu, Yan, Schneider-Futschik, Elena K., Hu, Xiaohan, Zhou, Qi Tony, Lin, Yu-Wei, Anderson, Dovile, Creek, Darren J., Hoyer, Daniel, Li, Jian, Velkov, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280556/
https://www.ncbi.nlm.nih.gov/pubmed/30546859
http://dx.doi.org/10.1016/j.csbj.2018.11.001

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