Cargando…
HOPX homeobox methylation in differentiated thyroid cancer and its clinical relevance
BACKGROUND: The inactivation of the tumor-suppressor homeodomain-only protein X (HOPX) usually involves promoter methylation in several cancer types. This study aimed to investigate the HOPX-β mRNA expression and promoter methylation and their clinical relevance in differentiated thyroid cancer (DTC...
Autores principales: | Lima, Erika Urbano, Rubio, Ileana G S, Da Silva, Joaquim Custodio, Galrão, Ana Luiza, Pêssoa, Danielle, Oliveira, Taise Cerqueira, Carrijo, Fabiane, Silva Campos, Igor, Fonseca Espinheira, Luciano, Sampaio, Luiz Jose, Lima, Claudio Rogerio, Cerutti, Janete Maria, Ramos, Helton Estrela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280589/ https://www.ncbi.nlm.nih.gov/pubmed/30400039 http://dx.doi.org/10.1530/EC-18-0380 |
Ejemplares similares
-
Association between BRAF (V600E) mutation and clinicopathological features of papillary thyroid carcinoma: a Brazilian single-centre case series
por: Pessôa-Pereira, Danielle, et al.
Publicado: (2019) -
The Homeobox Only Protein Homeobox (HOPX) and Colorectal Cancer
por: Yamashita, Keishi, et al.
Publicado: (2013) -
Transcriptional regulation of the potential tumor suppressor ABI3 gene in thyroid carcinomas: interplay between methylation and NKX2-1 availability
por: Moraes, Lais, et al.
Publicado: (2016) -
Preoperative detection of TERT promoter and BRAF(V600E) mutations in papillary thyroid carcinoma in high-risk thyroid nodules
por: Giorgenon, Tatiana Marina Vieira, et al.
Publicado: (2019) -
HOPX Is an Epigenetically Inactivated Tumor Suppressor and Overexpression of HOPX Induce Apoptosis and Cell Cycle Arrest in Breast Cancer
por: You, Qinghua, et al.
Publicado: (2020)