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Effective Therapy Using a Liposomal siRNA that Targets the Tumor Vasculature in a Model Murine Breast Cancer with Lung Metastasis

Although metastatic cancer is a major cause of death for cancer patients, no efficacious treatment for metastasis is available. We previously showed that the growth of a primary tumor could be inhibited by the administration of an anti-angiogenic small interfering RNA (siRNA) that is encapsulated in...

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Detalles Bibliográficos
Autores principales: Sakurai, Yu, Hada, Tomoya, Kato, Akari, Hagino, Yuta, Mizumura, Wataru, Harashima, Hideyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280606/
https://www.ncbi.nlm.nih.gov/pubmed/30534584
http://dx.doi.org/10.1016/j.omto.2018.10.004