Quantification of somatic mutation flow across individual cell division events by lineage sequencing

Mutation data reveal the dynamic equilibrium between DNA damage and repair processes in cells and are indispensable to the understanding of age-related diseases, tumor evolution, and the acquisition of drug resistance. However, available genome-wide methods have a limited ability to resolve rare som...

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Detalles Bibliográficos
Autores principales: Brody, Yehuda, Kimmerling, Robert J., Maruvka, Yosef E., Benjamin, David, Elacqua, Joshua J., Haradhvala, Nicholas J., Kim, Jaegil, Mouw, Kent W., Frangaj, Kristjana, Koren, Amnon, Getz, Gad, Manalis, Scott R., Blainey, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280753/
https://www.ncbi.nlm.nih.gov/pubmed/30459213
http://dx.doi.org/10.1101/gr.238543.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280753/
https://www.ncbi.nlm.nih.gov/pubmed/30459213
http://dx.doi.org/10.1101/gr.238543.118

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