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Agglomerated novel spray-dried lactose-leucine tailored as a carrier to enhance the aerosolization performance of salbutamol sulfate from DPI formulations
Spray-drying allows to modify the physicochemical/mechanical properties of particles along with their morphology. In the present study, (L)-leucine with varying concentrations (0.1, 0.5, 1, 5, and 10% w/v) were incorporated into lactose monohydrate solution for spray-drying to enhance the aerosoliza...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280810/ https://www.ncbi.nlm.nih.gov/pubmed/29260462 http://dx.doi.org/10.1007/s13346-017-0462-8 |