Cargando…

Transcatheter aortic valve replacement with balloon-expandable valve : Analysis of initial experience in China

BACKGROUND: Transcatheter aortic valve replacement (TAVR) is widely applied for the treatment of severe aortic stenosis (AS) in developed countries; however, in China, it is still in the early stage of utilization. On the basis of previous studies, this work explored the feasibility of TAVR in patie...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Y., Zhang, H., Zhang, L., Li, H., Mao, H., Pei, Y., Jing, Z., Lu, Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280821/
https://www.ncbi.nlm.nih.gov/pubmed/29236149
http://dx.doi.org/10.1007/s00059-017-4622-x
_version_ 1783378742474702848
author Shen, Y.
Zhang, H.
Zhang, L.
Li, H.
Mao, H.
Pei, Y.
Jing, Z.
Lu, Q.
author_facet Shen, Y.
Zhang, H.
Zhang, L.
Li, H.
Mao, H.
Pei, Y.
Jing, Z.
Lu, Q.
author_sort Shen, Y.
collection PubMed
description BACKGROUND: Transcatheter aortic valve replacement (TAVR) is widely applied for the treatment of severe aortic stenosis (AS) in developed countries; however, in China, it is still in the early stage of utilization. On the basis of previous studies, this work explored the feasibility of TAVR in patients with severe AS in China and analyzed the cause of death in four cases. METHODS: This retrospective study included 20 patients who had severe AS and underwent TAVR with a balloon-expandable system (Edwards SAPIEN XT) in our hospital from January 2011 to June 2016. The valve and heart functions of 16 survivors before and after the TAVR procedure were compared. TAVR endpoints, device success, and adverse events were assessed according to the definitions of the Valve Academic Research Consortium-2 (VARC-2). RESULTS: There were 13 male and seven female patients aged 65–81 years (average, 73.15) who underwent TAVR. The TAVR approach was transfemoral in 19 patients and transapical in one patient. Four patients died (two of coronary artery occlusion and two of aortic annulus rupture) during the TAVR procedure or shortly after; six patients had mild paravalvular leakage, and the rest of the patients showed a significant improvement in cardiac function. During the follow-up period (2–62 months), one patient died of lung cancer 13 months after the TAVR procedure. CONCLUSION: TAVR with a balloon-expandable system is safe and effective and can be used for patients with severe AS in China. It requires careful patient selection and preoperative assessment so as to reduce the 30-day postoperative mortality rate.
format Online
Article
Text
id pubmed-6280821
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Springer Medizin
record_format MEDLINE/PubMed
spelling pubmed-62808212018-12-26 Transcatheter aortic valve replacement with balloon-expandable valve : Analysis of initial experience in China Shen, Y. Zhang, H. Zhang, L. Li, H. Mao, H. Pei, Y. Jing, Z. Lu, Q. Herz Original Articles BACKGROUND: Transcatheter aortic valve replacement (TAVR) is widely applied for the treatment of severe aortic stenosis (AS) in developed countries; however, in China, it is still in the early stage of utilization. On the basis of previous studies, this work explored the feasibility of TAVR in patients with severe AS in China and analyzed the cause of death in four cases. METHODS: This retrospective study included 20 patients who had severe AS and underwent TAVR with a balloon-expandable system (Edwards SAPIEN XT) in our hospital from January 2011 to June 2016. The valve and heart functions of 16 survivors before and after the TAVR procedure were compared. TAVR endpoints, device success, and adverse events were assessed according to the definitions of the Valve Academic Research Consortium-2 (VARC-2). RESULTS: There were 13 male and seven female patients aged 65–81 years (average, 73.15) who underwent TAVR. The TAVR approach was transfemoral in 19 patients and transapical in one patient. Four patients died (two of coronary artery occlusion and two of aortic annulus rupture) during the TAVR procedure or shortly after; six patients had mild paravalvular leakage, and the rest of the patients showed a significant improvement in cardiac function. During the follow-up period (2–62 months), one patient died of lung cancer 13 months after the TAVR procedure. CONCLUSION: TAVR with a balloon-expandable system is safe and effective and can be used for patients with severe AS in China. It requires careful patient selection and preoperative assessment so as to reduce the 30-day postoperative mortality rate. Springer Medizin 2017-12-13 2018 /pmc/articles/PMC6280821/ /pubmed/29236149 http://dx.doi.org/10.1007/s00059-017-4622-x Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Articles
Shen, Y.
Zhang, H.
Zhang, L.
Li, H.
Mao, H.
Pei, Y.
Jing, Z.
Lu, Q.
Transcatheter aortic valve replacement with balloon-expandable valve : Analysis of initial experience in China
title Transcatheter aortic valve replacement with balloon-expandable valve : Analysis of initial experience in China
title_full Transcatheter aortic valve replacement with balloon-expandable valve : Analysis of initial experience in China
title_fullStr Transcatheter aortic valve replacement with balloon-expandable valve : Analysis of initial experience in China
title_full_unstemmed Transcatheter aortic valve replacement with balloon-expandable valve : Analysis of initial experience in China
title_short Transcatheter aortic valve replacement with balloon-expandable valve : Analysis of initial experience in China
title_sort transcatheter aortic valve replacement with balloon-expandable valve : analysis of initial experience in china
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280821/
https://www.ncbi.nlm.nih.gov/pubmed/29236149
http://dx.doi.org/10.1007/s00059-017-4622-x
work_keys_str_mv AT sheny transcatheteraorticvalvereplacementwithballoonexpandablevalveanalysisofinitialexperienceinchina
AT zhangh transcatheteraorticvalvereplacementwithballoonexpandablevalveanalysisofinitialexperienceinchina
AT zhangl transcatheteraorticvalvereplacementwithballoonexpandablevalveanalysisofinitialexperienceinchina
AT lih transcatheteraorticvalvereplacementwithballoonexpandablevalveanalysisofinitialexperienceinchina
AT maoh transcatheteraorticvalvereplacementwithballoonexpandablevalveanalysisofinitialexperienceinchina
AT peiy transcatheteraorticvalvereplacementwithballoonexpandablevalveanalysisofinitialexperienceinchina
AT jingz transcatheteraorticvalvereplacementwithballoonexpandablevalveanalysisofinitialexperienceinchina
AT luq transcatheteraorticvalvereplacementwithballoonexpandablevalveanalysisofinitialexperienceinchina