Germline BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance associated with breast/ovarian cancer: a report from North India

BACKGROUND: The spectrum of BRCA mutations that predispose to development of breast/ovarian cancer in Indian population remains unexplored. We report incidence and various types of pathogenic, likely pathogenic and variants of unknown significance (VUS) mutations in BRCA1 and BRCA2 genes observed at...

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Detalles Bibliográficos
Autores principales: Mehta, Anurag, Vasudevan, Smreti, Sharma, Sanjeev Kumar, Kumar, Dushyant, Panigrahi, Manoj, Suryavanshi, Moushumi, Gupta, Garima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280886/
https://www.ncbi.nlm.nih.gov/pubmed/30555256
http://dx.doi.org/10.2147/CMAR.S186563

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