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Population pharmacokinetic modeling of flurbiprofen, the active metabolite of flurbiprofen axetil, in Chinese patients with postoperative pain
BACKGROUND: Flurbiprofen axetil, a lipid-microsphere-carrier targeting preparation, is a non-steroidal anti-inflammatory drug indicated for the treatment of postoperative pain. AIM: The aim of the study was to develop a population pharmacokinetic (PPK) model of flurbiprofen, the active metabolite of...
Autores principales: | Zhang, Jingru, Zhang, Hong, Zhao, Libo, Gu, Jian, Feng, Yi, An, Haiyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280896/ https://www.ncbi.nlm.nih.gov/pubmed/30555252 http://dx.doi.org/10.2147/JPR.S176475 |
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