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Crystal structures of 3-methoxy-4-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methoxy}benzonitrile and N-(4-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide
The title compounds, C(18)H(15)N(3)O(4) and C(17)H(14)ClN(3)O(3), are heterocyclic 1,3,4-oxadiazole derivatives which differ from each other in the groups attached to the carbon atoms: a methoxyphenyl ring and a benzonitrile group in (I) and a chlorophenyl ring and an acetamide group in (II). S...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281121/ https://www.ncbi.nlm.nih.gov/pubmed/30574401 http://dx.doi.org/10.1107/S2056989018016754 |
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author | Lakshmithendral, K. Archana, K. Saravanan, K. Kabilan, S. Selvanayagam, S. |
author_facet | Lakshmithendral, K. Archana, K. Saravanan, K. Kabilan, S. Selvanayagam, S. |
author_sort | Lakshmithendral, K. |
collection | PubMed |
description | The title compounds, C(18)H(15)N(3)O(4) and C(17)H(14)ClN(3)O(3), are heterocyclic 1,3,4-oxadiazole derivatives which differ from each other in the groups attached to the carbon atoms: a methoxyphenyl ring and a benzonitrile group in (I) and a chlorophenyl ring and an acetamide group in (II). Short intramolecular C—H⋯O hydrogen bonds occur in both molecules. The crystal structure of (I) features C—H⋯N hydrogen bonds, while in the crystal structure of (II), N—H⋯N, C—H⋯N and C—H⋯O hydrogen bonds are observed. |
format | Online Article Text |
id | pubmed-6281121 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-62811212018-12-20 Crystal structures of 3-methoxy-4-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methoxy}benzonitrile and N-(4-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide Lakshmithendral, K. Archana, K. Saravanan, K. Kabilan, S. Selvanayagam, S. Acta Crystallogr E Crystallogr Commun Research Communications The title compounds, C(18)H(15)N(3)O(4) and C(17)H(14)ClN(3)O(3), are heterocyclic 1,3,4-oxadiazole derivatives which differ from each other in the groups attached to the carbon atoms: a methoxyphenyl ring and a benzonitrile group in (I) and a chlorophenyl ring and an acetamide group in (II). Short intramolecular C—H⋯O hydrogen bonds occur in both molecules. The crystal structure of (I) features C—H⋯N hydrogen bonds, while in the crystal structure of (II), N—H⋯N, C—H⋯N and C—H⋯O hydrogen bonds are observed. International Union of Crystallography 2018-11-30 /pmc/articles/PMC6281121/ /pubmed/30574401 http://dx.doi.org/10.1107/S2056989018016754 Text en © Lakshmithendral et al. 2018 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/2.0/uk/ |
spellingShingle | Research Communications Lakshmithendral, K. Archana, K. Saravanan, K. Kabilan, S. Selvanayagam, S. Crystal structures of 3-methoxy-4-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methoxy}benzonitrile and N-(4-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide |
title | Crystal structures of 3-methoxy-4-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methoxy}benzonitrile and N-(4-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide |
title_full | Crystal structures of 3-methoxy-4-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methoxy}benzonitrile and N-(4-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide |
title_fullStr | Crystal structures of 3-methoxy-4-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methoxy}benzonitrile and N-(4-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide |
title_full_unstemmed | Crystal structures of 3-methoxy-4-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methoxy}benzonitrile and N-(4-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide |
title_short | Crystal structures of 3-methoxy-4-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methoxy}benzonitrile and N-(4-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide |
title_sort | crystal structures of 3-methoxy-4-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methoxy}benzonitrile and n-(4-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide |
topic | Research Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281121/ https://www.ncbi.nlm.nih.gov/pubmed/30574401 http://dx.doi.org/10.1107/S2056989018016754 |
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