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Optimization of self-microemulsifying drug delivery system for phospholipid complex of telmisartan using D-optimal mixture design
To improve the dissolution behavior of telmisartan (TMS), a poorly water-soluble angiotensin II receptor blocker, TMS-phospholipid complex (TPC) was prepared by solvent evaporation method and characterized by differential scanning calorimetry and powder X-ray diffractometry. The crystalline structur...
Autores principales: | Son, Ho Yong, Chae, Bo Ram, Choi, Ji Yeh, Shin, Dong Jun, Goo, Yoon Tae, Lee, Eun Seok, Kang, Tae Hoon, Kim, Chang Hyun, Yoon, Ho Yub, Choi, Young Wook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281252/ https://www.ncbi.nlm.nih.gov/pubmed/30517187 http://dx.doi.org/10.1371/journal.pone.0208339 |
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