Analysis of NK cell clones obtained using interleukin-2 and gene-modified K562 cells revealed the ability of “senescent” NK cells to lose CD57 expression and start expressing NKG2A

In this work, we analyzed the phenotype and growth of human NK cell clones obtained by the stimulation of individual NK cells with IL-2 and gene-modified K562 feeder cells expressing membrane-bound IL-21 (K562-mbIL21). We generated clones from NK cells at distinct differentiation and activation stag...

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Detalles Bibliográficos
Autores principales: Streltsova, Maria A., Erokhina, Sofya A., Kanevskiy, Leonid M., Lee, Dean A., Telford, William G., Sapozhnikov, Alexander M., Kovalenko, Elena I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281266/
https://www.ncbi.nlm.nih.gov/pubmed/30517188
http://dx.doi.org/10.1371/journal.pone.0208469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281266/
https://www.ncbi.nlm.nih.gov/pubmed/30517188
http://dx.doi.org/10.1371/journal.pone.0208469

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