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Preliminary development of an assay for detection of TERT expression, telomere length, and telomere elongation in single cells
The telomerase enzyme enables unlimited proliferation of most human cancer cells by elongating telomeres and preventing replicative senescence. Despite the critical importance of telomerase in cancer biology, challenges detecting telomerase activity and expression in individual cells have hindered t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281304/ https://www.ncbi.nlm.nih.gov/pubmed/30517099 http://dx.doi.org/10.1371/journal.pone.0206525 |