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Preliminary development of an assay for detection of TERT expression, telomere length, and telomere elongation in single cells

The telomerase enzyme enables unlimited proliferation of most human cancer cells by elongating telomeres and preventing replicative senescence. Despite the critical importance of telomerase in cancer biology, challenges detecting telomerase activity and expression in individual cells have hindered t...

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Detalles Bibliográficos
Autores principales:	Ravindranathan, Ajay, Cimini, Beth, Diolaiti, Morgan E., Stohr, Bradley A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281304/ https://www.ncbi.nlm.nih.gov/pubmed/30517099 http://dx.doi.org/10.1371/journal.pone.0206525

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