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Glucose intake hampers PKA-regulated HSP90 chaperone activity

Aging is an intricate phenomenon associated with the gradual loss of physiological functions, and both nutrient sensing and proteostasis control lifespan. Although multiple approaches have facilitated the identification of candidate genes that govern longevity, the molecular mechanisms that link agi...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Chen, Jiang, Pei-Heng, Chen, Hsuan-Ming, Chen, Chang-Han, Wang, Yi-Ting, Chen, Yu-Ju, Yu, Chia-Jung, Teng, Shu-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281317/
https://www.ncbi.nlm.nih.gov/pubmed/30516470
http://dx.doi.org/10.7554/eLife.39925