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Spliceosome factors target timeless (tim) mRNA to control clock protein accumulation and circadian behavior in Drosophila

Transcription-translation feedback loops that comprise eukaryotic circadian clocks rely upon temporal delays that separate the phase of active transcription of clock genes, such as Drosophila period (per) and timeless (tim), from negative feedback by the two proteins. However, our understanding of t...

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Detalles Bibliográficos
Autores principales: Shakhmantsir, Iryna, Nayak, Soumyashant, Grant, Gregory R, Sehgal, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281371/
https://www.ncbi.nlm.nih.gov/pubmed/30516472
http://dx.doi.org/10.7554/eLife.39821