Bismuth Toxicity Presenting as Declining Mobility and Falls

A 77-year old woman presented with a history of falls. Known health problems included biopsy-proven collagenous colitis treated with bismuth subsalicylate. On examination, in addition to impaired balance and gait, she was found to have tremors and cognitive deficits. Investigations revealed a marked...

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Detalles Bibliográficos
Autores principales: Hogan, David B., Harbidge, Cathy, Duncan, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Canadian Geriatrics Society 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281375/
https://www.ncbi.nlm.nih.gov/pubmed/30595782
http://dx.doi.org/10.5770/cgj.21.323
Descripción
Sumario:A 77-year old woman presented with a history of falls. Known health problems included biopsy-proven collagenous colitis treated with bismuth subsalicylate. On examination, in addition to impaired balance and gait, she was found to have tremors and cognitive deficits. Investigations revealed a markedly elevated urinary bismuth level. Withdrawal of bismuth subsalicylate led to marked cognitive and physical improvement.

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