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Human liver stem cell-derived extracellular vesicles enhance cancer stem cell sensitivity to tyrosine kinase inhibitors through Akt/mTOR/PTEN combined modulation

It is well recognized that Cancer Stem Cells (CSCs) sustain the initiation, the maintenance and the recurrence of tumors. We previously reported that extracellular vesicles (EVs) derived from human liver stem cells (HLSCs) were able to limit tumor development. In this study, we evaluated whether EV...

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Detalles Bibliográficos
Autores principales:	Fonsato, Valentina, De Lena, Michela, Tritta, Stefania, Brossa, Alessia, Calvetti, Ruggero, Tetta, Ciro, Camussi, Giovanni, Bussolati, Benedetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281417/ https://www.ncbi.nlm.nih.gov/pubmed/30546834 http://dx.doi.org/10.18632/oncotarget.26319

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