Cargando…

Microtubule nucleation by γ-tubulin complexes and beyond

In this short review, we give an overview of microtubule nucleation within cells. It is nearly 30 years since the discovery of γ-tubulin, a member of the tubulin superfamily essential for proper microtubule nucleation in all eukaryotes. γ-tubulin associates with other proteins to form multiprotein γ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tovey, Corinne A., Conduit, Paul T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281477/ https://www.ncbi.nlm.nih.gov/pubmed/30315097 http://dx.doi.org/10.1042/EBC20180028

Ejemplares similares

Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes
por: Zhu, Zihan, et al.
Publicado: (2023)

γ-Tubulin complexes in microtubule nucleation and beyond
por: Oakley, Berl R., et al.
Publicado: (2015)

γ-Tubulin in microtubule nucleation and beyond
por: Sulimenko, Vadym, et al.
Publicado: (2022)

Microtubule stabilization in vivo by nucleation-incompetent γ-tubulin complex
por: Anders, Andreas, et al.
Publicado: (2011)

Autoinhibition of Cnn binding to γ-TuRCs prevents ectopic microtubule nucleation and cell division defects
por: Tovey, Corinne A., et al.
Publicado: (2021)

c-Abl kinase-mediated phosphorylation of γ-tubulin promotes γ-tubulin ring complexes assembly and microtubule nucleation
por: Wang, Guang-Fei, et al.
Publicado: (2022)

Characterization of Two Related Drosophila γ-tubulin Complexes that Differ in Their Ability to Nucleate Microtubules
por: Oegema, Karen, et al.
Publicado: (1999)

CDK5RAP2 stimulates microtubule nucleation by the γ-tubulin ring complex
por: Choi, Yuk-Kwan, et al.
Publicado: (2010)

γ-Tubulin 2 Nucleates Microtubules and Is Downregulated in Mouse Early Embryogenesis
por: Vinopal, Stanislav, et al.
Publicado: (2012)

XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions
por: King, Brianna R., et al.
Publicado: (2020)

An extended γ-tubulin ring functions as a stable platform in microtubule nucleation
por: Erlemann, Sarah, et al.
Publicado: (2012)

Drosophila melanogaster γ-TuRC is dispensable for targeting γ-tubulin to the centrosome and microtubule nucleation
por: Vérollet, Christel, et al.
Publicado: (2006)

Correction: γ-Tubulin 2 Nucleates Microtubules and Is Downregulated in Mouse Early Embryogenesis
por: Vinopal, Stanislav, et al.
Publicado: (2012)

Virtual and Biophysical Screening Targeting the γ-Tubulin Complex – A New Target for the Inhibition of Microtubule Nucleation
por: Cala, Olivier, et al.
Publicado: (2013)

CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation
por: Brilot, Axel F, et al.
Publicado: (2021)

MOZART1 and γ-tubulin complex receptors are both required to turn γ-TuSC into an active microtubule nucleation template
por: Lin, Tien-chen, et al.
Publicado: (2016)

Microtubules form by progressively faster tubulin accretion, not by nucleation–elongation
por: Rice, Luke M., et al.
Publicado: (2021)

The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle
por: Chinen, Takumi, et al.
Publicado: (2015)

Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding
Publicado: (1985)

CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation
por: Imasaki, Tsuyoshi, et al.
Publicado: (2022)

The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC)
por: Rale, Michael J, et al.
Publicado: (2022)

XMAP215 is a microtubule nucleation factor that functions synergistically with the gamma-tubulin ring complex
por: Thawani, Akanksha, et al.
Publicado: (2018)

Efficient formation of bipolar microtubule bundles requires microtubule-bound γ-tubulin complexes
por: Janson, Marcel E., et al.
Publicado: (2005)

GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation
por: Ayukawa, Rie, et al.
Publicado: (2021)

When Overexpressed, a Novel Centrosomal Protein, RanBPM, Causes Ectopic Microtubule Nucleation Similar to γ-Tubulin
por: Nakamura, Masafumi, et al.
Publicado: (1998)

γ-Tubulin ring complexes regulate microtubule plus end dynamics
por: Bouissou, Anaïs, et al.
Publicado: (2009)

The Role of γ-Tubulin in Centrosomal Microtubule Organization
por: O'Toole, Eileen, et al.
Publicado: (2012)

Cell Edges Accumulate Gamma Tubulin Complex Components and Nucleate Microtubules following Cytokinesis in Arabidopsis thaliana
por: Ambrose, Chris, et al.
Publicado: (2011)

Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules
por: Song, Jae-Geun, et al.
Publicado: (2018)

Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase
por: Hernández-Vega, Amayra, et al.
Publicado: (2017)

Microtubule organization: A complex solution
por: Conduit, Paul T.
Publicado: (2016)

Correction: The Role of γ-Tubulin in Centrosomal Microtubule Organization
por: O'Toole, Eileen, et al.
Publicado: (2012)

Assembly and regulation of γ-tubulin complexes
por: Farache, Dorian, et al.
Publicado: (2018)

Microtubule dynamics investigated by microinjection of Paramecium axonemal tubulin: lack of nucleation but proximal assembly of microtubules at the kinetochore during prometaphase
Publicado: (1989)

Polyamine Sharing between Tubulin Dimers Favours Microtubule Nucleation and Elongation via Facilitated Diffusion
por: Mechulam, Alain, et al.
Publicado: (2009)

Modular assembly of the principal microtubule nucleator γ-TuRC
por: Würtz, Martin, et al.
Publicado: (2022)

Human chromosomes and centrioles as nucleating sites for the in vitro assembly of microtubules from bovine brain tubulin
Publicado: (1975)

A Comprehensive Study on the Electrostatic Properties of Tubulin-Tubulin Complexes in Microtubules
por: Guo, Wenhan, et al.
Publicado: (2023)

Tubulin but not microtubule
por: Dove, Alan W.
Publicado: (2002)

Microtubule nucleating γTuSC assembles structures with 13-fold microtubule-like symmetry
por: Kollman, Justin M., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_t7v3e68lsri9j76nqohkbr6fqb