Cargando…

Cryopreservation of primary B cells minimally influences their signaling responses

Phospho flow is a powerful approach to detect cell signaling aberrations, identify biomarkers and assess pharmacodynamics, and can be performed using cryopreserved samples. The effects of cryopreservation on signaling responses and the reproducibility of phospho flow measurements are however unknown...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hermansen, Johanne U., Tjønnfjord, Geir E., Munthe, Ludvig A., Taskén, Kjetil, Skånland, Sigrid S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281576/ https://www.ncbi.nlm.nih.gov/pubmed/30518828 http://dx.doi.org/10.1038/s41598-018-36121-9

Ejemplares similares

Single cell profiling of phospho-protein levels in chronic lymphocytic leukemia
por: Myhrvold, Ida K., et al.
Publicado: (2018)

A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine
por: Hermansen, Johanne U., et al.
Publicado: (2023)

Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically
por: Giliberto, Mariaserena, et al.
Publicado: (2022)

P613: ANALYSIS OF EX-VIVO RESPONSE TO SINGLE DRUGS AND DRUG COMBINATIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA PATIENT SAMPLES
por: Miranda Santana, Leonardo, et al.
Publicado: (2023)

Functional testing of relapsed chronic lymphocytic leukemia guides precision medicine and maps response and resistance mechanisms. An index case
por: Skånland, Sigrid S., et al.
Publicado: (2022)

Mcl‐1 and Bcl‐xL levels predict responsiveness to dual MEK/Bcl‐2 inhibition in B‐cell malignancies
por: Melvold, Katrine, et al.
Publicado: (2021)

Determining drug dose in the era of targeted therapies: playing it (un)safe?
por: Skånland, Sigrid S., et al.
Publicado: (2022)

Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice
por: Ruffini, Pier Adelchi, et al.
Publicado: (2014)

Standardized assays to monitor drug sensitivity in hematologic cancers
por: Ayuda-Durán, Pilar, et al.
Publicado: (2023)

T‐helper cell regulation of CD45 phosphatase activity by galectin‐1 and CD43 governs chronic lymphocytic leukaemia proliferation
por: Imbery, John F., et al.
Publicado: (2022)

S144: BTK AND BCL-2 ACTIVITY AT BASELINE PREDICTS MRD STATUS FOR CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS TREATED WITH IBRUTINIB + VENETOCLAX IN THE HOVON 141/VISION TRIAL
por: Urban, Aleksandra, et al.
Publicado: (2023)

Successful Control of Hepatitis B Virus Reactivation following Restart of Ibrutinib in Chronic Lymphocytic Leukaemia
por: Tjønnfjord, Sara Kristina Viberg, et al.
Publicado: (2021)

Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
por: Giliberto, Mariaserena, et al.
Publicado: (2022)

Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells – Role of Anchored Protein Kinase A Signaling Units
por: Wehbi, Vanessa L., et al.
Publicado: (2016)

Spatiotemporal regulation of cAMP signaling controls the human trophoblast fusion
por: Gerbaud, Pascale, et al.
Publicado: (2015)

Primary chronic cold agglutinin disease: An update on pathogenesis, clinical features and therapy
por: Berentsen, Sigbjørn, et al.
Publicado: (2007)

B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells
por: Huszthy, Peter Csaba, et al.
Publicado: (2019)

Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination
por: Schultz, Nina H., et al.
Publicado: (2021)

Springboard to an academic career—A national medical student research program
por: Jacobsen, Geir W., et al.
Publicado: (2018)

USF2 inhibits C/EBP-mediated transcriptional regulation of the RIIβ subunit of cAMP-dependent protein kinase
por: Dahle, Maria Krudtaa, et al.
Publicado: (2002)

PI3K inhibitors in chronic lymphocytic leukemia: where do we go from here?
por: Skånland, Sigrid S., et al.
Publicado: (2022)

Anchored PKA as a gatekeeper for gap junctions
por: Pidoux, Guillaume, et al.
Publicado: (2015)

Minimizing the deleterious effects of endophytes in plant shoot tip cryopreservation
por: Volk, Gayle M., et al.
Publicado: (2022)

Proinflammatory and Immunoregulatory Roles of Eicosanoids in T Cells
por: Lone, Anna Mari, et al.
Publicado: (2013)

Targeting protein–protein interactions in complexes organized by A kinase anchoring proteins
por: Calejo, Ana I., et al.
Publicado: (2015)

A national intercalated medical student research program – student perceptions, satisfaction, and factors associated with pursuing a PhD
por: Sandvei, Marie Søfteland, et al.
Publicado: (2022)

SNX4 in Complex with Clathrin and Dynein: Implications for Endosome Movement
por: Skånland, Sigrid S., et al.
Publicado: (2009)

Targeting Tuberculosis and HIV Infection-Specific Regulatory T Cells with MEK/ERK Signaling Pathway Inhibitors
por: Lieske, Nora V., et al.
Publicado: (2015)

Factor eight inhibitor bypass activity (FEIBA) in the management of bleeds in hemophilia patients with high-titer inhibitors
por: Tjønnfjord, Geir E, et al.
Publicado: (2007)

The a-Kinase–Anchoring Protein Akap95 Is a Multivalent Protein with a Key Role in Chromatin Condensation at Mitosis
por: Collas, Philippe, et al.
Publicado: (1999)

Degradation of methylation signals in cryopreserved DNA
por: Lee, Ning Yuan, et al.
Publicado: (2023)

Cytokinesis arrest and multiple centrosomes in B cell chronic lymphocytic leukaemia
por: Rogne, Marie, et al.
Publicado: (2018)

Polyproline as a Minimal Antifreeze Protein Mimic That Enhances the Cryopreservation of Cell Monolayers
por: Graham, Ben, et al.
Publicado: (2017)

Maternal and obstetric outcomes are influenced by developmental stage and cryopreservation of transferred embryos after clomiphene citrate-based minimal stimulation IVF
por: Onogi, Sachie, et al.
Publicado: (2022)

Comparative cryopreservation of bovine and porcine primary hepatocytes
por: Andres, Sandra, et al.
Publicado: (2023)

Interplay between the heterotrimeric G-protein subunits G(αq )and G(αi2 )sets the threshold for chemotaxis and TCR activation
por: Ngai, Jacob, et al.
Publicado: (2009)

Novel ZEB2-BCL11B Fusion Gene Identified by RNA-Sequencing in Acute Myeloid Leukemia with t(2;14)(q22;q32)
por: Torkildsen, Synne, et al.
Publicado: (2015)

National trends in incidence and survival of chronic lymphocytic leukemia in Norway for 1953–2012: a systematic analysis of population‐based data
por: Lenartova, Andrea, et al.
Publicado: (2016)

Autologous oocyte cryopreservation in women aged 40 and older using minimal stimulation IVF
por: Zhang, John J., et al.
Publicado: (2015)

Oocyte cryopreservation review: outcomes of medical oocyte cryopreservation and planned oocyte cryopreservation
por: Walker, Zachary, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6lot2g34vjtim3g33c7703jj4r